Two new beta carboline type alkaloids from Dicorynia guianensisheartwood

Jean-Baptiste Say Anouhe , Augustin Adima (1) , Florence Bobele Niamke (1) , Didier Stien , Brice Kassi Amian (1) , Pierre-Alain Blandinières (2) , David Null Virieux (3) , S. Kati-Coulibaly (1) , Jean-Luc Pirat (3) , Nadine Amusant (2)

1 INPHB - Groupe de recherche en Chimie des Eaux et des Substances Naturelles, Institut National Polytechnique Houphoue¨t Boigny, BP 1313 Yamoussoukro, Cote d’Ivoire
2 UMR ECOFOG - Ecologie des forêts de Guyane
3 ICGM - Institut Charles Gerhardt Montpellier - Institut de Chimie Moléculaire et des Matériaux de Montpellier

The chemical investigations of Dicorynia guianensis heartwood led to the isolation of four new indole alkaloids for the first time in this plant. Compound (1) identified as spiroindolone 20,30,40,90-tetrahydrospiro [indoline-3,10pyrido[3,4-b]-indol]-2-one, and compound (3) described as nitrone 1-methyl-4,9-dihydro-3H-pyrido [3,4-b] indole 2-oxide and were isolated for the first time as natural products. ABTS antioxidant activity guided their isolation.

Mots clés: Nitrone ABTS; antioxidant; Dicorynia guianensis; Biogenesis; Spiroindolone

Domaines: Chimie; Sciences de l'environnement

Jean-Baptiste Say Anouhe, Augustin Adima, Florence Bobele Niamke, Didier Stien, Brice Kassi Amian, et al.. Two new beta carboline type alkaloids from Dicorynia guianensisheartwood. Phytochemistry Letters, 2015, pp.xxx-xxx. ⟨10.1016/j.phytol.2015.03⟩. ⟨hal-01138910⟩